Applications for Stem Cells in Ophthalmology
Stem cell therapy is a new invention in the field of medical science. The study of stem cell hasrevealed that the use of autologous bone marrow derived stem cells (BMSC) is perfect for the treatment of retinal and optic nerve damage or disease.Adult ocular stem cells have the potential to reinstate vision in patients previously deemed incurable. Below are the diseases, which are treated through stem cell therapy.
- Retinal Disease
- Macular Degeneration
- Hereditary Retinal Dystrophy
- Optic Nerve Disease
The Department of Ophthalmology copes with the physiology, structure, anatomy and sicknesses related to the eyes. Ophthalmologists have the proficiency to treat all types of eye related problems ranging from routine eye inspection to eye surgery and other disorders of the eye and surrounding structures. Our crew is fully fortified with state-of-the-art diagnostic and therapeutic equipment for treating glaucoma, cataracts, corneal ailments, aesthetics, paediatric ophthalmic ailments and sicknesses.
Cell injury or degeneration happens during a variety of glaring diseases. Medical care has classically consisted of preventing the initial injury or increasing the resistance of cells to injury (cytoprotection). Recently, it’s become attainable to repopulate tissue compartments with stem cells. Stem cells area unit de differentiated cells able to divide indefinitely nonetheless maintain the flexibility to differentiate into specific cell varieties. They’re able to survive throughout the lifespan of the organism, whereas maintaining their variety, manufacturing populations of female offspring cells (transit amplifying cells) which will proceed down distinctive pathways of differentiation. Stem cells are also obtained from embryonic tissues, canal blood, and a few differentiated adult tissues. though the potential for stem cell–based therapies for a spread of human diseases is promising, various issues stay to be overcome, like ways for getting, transplant, causing differentiation, developing operate, and eliminating immune reactions.1 Stem cells have nice potential worth in treating eye diseases characterized by irreversible loss of cells, like eye disease and photo receptor degeneration.
Although stem cells supply nice opportunities for repair of the nervous system and therefore the eye, their clinical use necessitates that we tend to initial gain associate degree understanding of their proliferation, migration, differentiation, immunogenicity and institution of practical cell contacts. It will even be necessary to provide these cells in conditions that meet acceptable safety and effectiveness standards. Our current understanding of the vital factors moving somatic cell behavior remains restricted. fast progress is being created, and a few of the primary applications of stem cells to wound repair inhuman eyes have created successes that provide hope for the utilization of stem cells in alternative ophthalmologic conditions. during this article, we tend to discuss current ideas in somatic cells and therefore the eye and measure stem cell medical care in eye disease as a paradigm for novel approaches to the treatment of disease. to get giant numbers of en grafted stem cells that differentiate during a desired method, ways area unit required to channel cells into desired phenotypes. Modification of the micro environment and/or inhibition of intracellular sign falls in en grafted cells are required for acceptable cell-specific differentiation into wounded tissue.