Do mesenchymal stem cells enhance risk of tumor?
The most petrifyingtrepidationabout mesenchymal stem cell treatment that certainly forces patients to desist from this kind of treatment is the uncertain risk of increasing the formation of cancerous tumors by the therapy. It is defendable in case of embryonic stem cell therapy where the cells divide uncontrollably and quicklyconsequentlyincreasing the risk as well as occurrence of cancer-causing tumors in animals and human beings. Purposeless to say that embryonic stem cell therapy is subsequently strictly barred by law in maximumcountries. At Viezec, we promise a cancer-risk free treatment as our treatment incorporates allogeneic stem cells which have verified to be non-carcinogenic. The following facts can clear your qualmson the topic of the cancer-causing prospective of the adult stem cell therapy:
Mesenchymal stem cells therapy does not lead to intensified tumor risk unless the patient is suffering from cancer before the treatment. These cells are moved shortly after withdrawal followed by purification and concentration for only therapeutic commitments. The following applies to therapy with Allogeneic/Adult Mesenchymal stem cells:
Allogeneic/Adult Mesenchymal stem cells, which are transplanted immediately after their removal and concentration for therapeutic purposes, do not increase the risk of tumor unless the patient already has cancer.
No signs of higher tumor development have been found to exist over the last 40 years in the therapy of leukemia and lymphoma, which also incorporates the use of adult stem cells.
The conduct of adult stem cells depends enormously on their surroundings. There is no proof to date that adult stem cells endorse tumor formation in the human body. There is one exception. The growth of an existing tumor can be endorsed by the addition of adult stem cells and tissue that is damaged by radioactivity can stabilize into cancerous tissue after the immunization of adult stem cells.
Adult stem cells only incline to form cancerous stem cells if they are permitted to reproduce in a culture dish over a lengthy period of time, since the probability of hereditary defect clusters increases in proportion to the number of cell divisions.
In a pre-clinical tumorogenicity study in mice, no amplified risk was found.
In line with the up-to-date scientific findings, the therapy implemented at our center does not cause tumors as the stem cells are mature cells (in difference with embryonic cells) and are not allowable to multiply for any length of time outside the body. They are moved back into the body instantly after purification. We don’t treat patients with tumors. Relying on the newest findings of modern-day research, we can firmly declare that our treatment does not increase the risk of tumors or cause them owing to the fact that we use adult stem cells instead of embryonic cells. We take every precaution to decline the cancer risks to zero by safeguarding stoppage of multiplication of cells because of immediate transplant post purification and concentration. Unfortunately, our policy strictly bans treatment of patients with cancerous as well as benevolent tumors.
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