What is Down Syndrome?
Down syndrome is a chromosomal ailment that causes injury inside the actual and cognitive development of a youngster. This is basically the most frequent basis for emotional retardation among kids. Those with Downward disorder experience normal functions, say, for example, a level face along with a brief neck and throat. These features bring all the differences inside the features individually for each person. It is a lifetime condition. Though with ideal attention and support, children with down disorder can get older to get a wholesome and prolific lifestyle. Down Syndrome Stem Cell Treatment in India can greatly support obtaining this prolific life attribute. Down disorder is instigated by an incidence of added chromosome 21. Chromosomes bring the genes that train the entire body to produce in certain methods as well as put into action particular characteristics. Maximum tissues of the human body encompass 23 sets of chromosomes, 1 list of chromosomes from each father or mother. Those that have Down syndrome have 47 chromosomes. Stem cell treatment aids as a tremendous help with Down trouble.
Possessing more or irregular chromosomes interrupts the conventional length of improvement and brings about the actual physical characteristics and intellectual and developmental in capabilities concerning the syndrome. The proper remedy for the underlying condition is stem cell treatment for Down disorder in India.
People are searching for stem cell Down Syndrome Treatment in Delhi, India, but can’t seem to find the best Down Syndrome Treatment hospitals at an affordable price. Viezec helps those patients to find the best hospitals for stem cell Down Syndrome Treatment in Delhi, India
Causes of Down Syndrome
Man tissue regularly consists of 23 groups of chromosomes. 1 chromosome in each set comes from your father and the other from your mommy. This extra genetic substance is liable for the brand illustrates and formative problems of the Lower condition. Any kind of three genetic versions may cause a condition:
Trisomy 21. Close to 95 percent of the time, a down ailment is a result of trisomy 21; the average person has three duplicates of chromosome 21, rather than regular two duplicates, in all of the tissue. This can be a result of strange cellular sections through the enhancement of the sperm cellular or maybe the ovum cellular.
Mosaic Down problem. Within this uncommon form of Down disorder, someone has only a few tissues with further identification of chromosome 21. This mosaic of every day and abnormal cells is caused by the strange cellular departments after treatment.
Translocation Down problem. the down ailment can likewise occur when a little bit of chromosome 21 becomes signed up with (translocated) onto another chromosome, previously or at origination. These teenagers have the typical two duplicates of chromosome 21, but they likewise have added inherited materials from chromosome 21 to become a member of another chromosome.
Symptoms Associated with The Down Syndrome
The most prevalent signs or symptoms witnessed in kids that are lower with down symptoms are:
- Unique facial capabilities like a toned face, slanting eye, little ear, simple neck, left arm and thighs and legs, and small mouth area.
- Individual, strong rumbles across the middle of the palm.
- Just one flexion furrow from the fifth finger.
- Decrease tone of muscle and wobbly joints.
- Listed below-typical astuteness.
Moreover, youngsters with down syndrome can be born with the cardiovascular system, intestinal tract, ears, or inhaling and exhaling issues. These problems often cause other problems like air passage bacterial infections or loss of hearing, for this reason. The most prevalent symptoms observed in youngsters which can be down with down issues are:
- Distinctive facial capabilities like a level experience, slanting eyes, modest ears, simple throat, arms and legs, and modest mouth.
- Solitary, deep rumples across the center of the palm.
- Just one flexion furrow of the 5th finger.
- Lower muscle mass and wobbly bones.
- Under-average astuteness.
Moreover, kids with Down symptoms can also be brought into this world with center, intestine, hearing, or inhaling and exhaling difficulties. These disorders often cause other problems, such as airway infections or hearing difficulties; for this reason, stem cell treatment for Down Syndrome in India is preferred.
What Are the Tests to Down Syndrome Diagnosis
A doctor may suspect Down syndrome in a newborn based on the baby’s appearance. A blood test can confirm, called a karyotype test, lines up the chromosomes and will show if there’s an extra chromosome 21.
Down Syndrome Screening in Pregnancy
Routine tests done during pregnancy can check if it’s likely your baby has Down syndrome. If those results are positive, or if you’re at high risk, you may choose to have additional, more invasive tests, to be specific.
In the first trimester, you may have:
- Blood tests. Your doctor will measure the levels of a protein called PAPP-A and a hormone called hCG in your blood. Anything out of the normal range could mean a problem with the baby. If you’re at high risk for Down syndrome, they may also look for DNA from the baby in your blood, which they can examine for chromosome abnormalities.
- Your doctor will look at a picture of your baby and measure the folds of tissue at the back of their neck. Babies with Down syndrome tend to have extra fluid there.
In the second trimester, you may have:
- Blood tests. A triple or quad-screen test measures other substances in your blood, including the protein AFP and the hormone estriol. Those levels, combined with the results from the first trimester tests, give your doctor a reasonable estimate of your baby’s chances of Down syndrome.
- When your baby is more developed, an enhanced ultrasound can show some of the physical features of Down syndrome.
Other kinds of tests can diagnose Down syndrome before your baby is born by checking a sample of their DNA for an extra chromosome 21:
- Chorionic villus sampling (CVS). This can be done during the first trimester using cells taken from the placenta.
- Fluid is taken from the amniotic sac surrounding the baby, usually during the second trimester.
- Percutaneous umbilical blood sampling (PUBS). This is also done in the second trimester using blood removed from the umbilical cord.
Kindly share the following test reports of
- Chromosomal Karyotyping (trisomy 21 karyotype Testing)
Stem Cell Treatment for Down Syndrome
The conventional treatment method approaches to aid in the management of associated signs and symptoms and will help improve the physical and cerebral aptitude of your kid, reestablishing the individual to daily life. Down stem cell treatment does quite the change; its goals are to stimulate the maintenance elements and treat the central impairment in the stressed cells combined with the management of impairments found in affected folks. Cellular treatment employing autologous bone marrow produced by mononuclear cells is recommended as a treatment method that befits several neurological conditions. These tissues have the propensity to migrate and present fixed components such as endogenous neurogenesis, angiogenesis, and synaptogenesis of your impaired neurons. As well as that, come cell therapies help greatly lessen inflammation and systemic immunological processes, thus augmenting the process of recovery.
Stem Cell Implantation for Down Syndrome
Stem cell implantation can be done in the following ways.
- Intravenous administration
- Intrathecal (lumber puncture)
- Intramuscular
- Intraarterial
- Subcutaneous
- Liberation angioplasty
- Surgical administration for stroke
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Improvements Seen After the Stem Cell Therapy for Down Syndrome
Down syndrome is a condition caused by an extra copy of chromosome 21. It is characterized by mental retardation, low muscle tone, an upward slant to the eyes, and a characteristic broad flat facial structure. However, currently, there is no known cure for Down syndrome. Medical research has shown that stem cell treatments can help improve conditions related to this very rare disorder, suggesting that there is hope that people with Down syndrome can be cured one day. Until then, they are using stem cells can at least lead to better lives, even if there isn’t a lasting solution.
Mechanism of Down Syndrome
The conventional treatment approaches to aid in the management of associated symptoms and helps improve the physical and intellectual aptitude of the kid, re-establishing the patient to daily life.
Researchers and doctors hope stem cell studies can help to increase awareness about how illnesses arise. Researchers and physicians may better understand how diseases and conditions grow by seeing stem cells mature into cells in bones, heart muscles, nerves, and other organs and tissues.
Cellular therapy using autologous bone marrow derived from mononuclear cells has been proposed as a treatment approach that befits numerous neurological ailments. These cells have the propensity to migrate and offer repair mechanisms such as endogenous neurogenesis, angiogenesis, and synaptogenesis of the impaired neurons. Along with that, stem cell therapy helps significantly decrease inflammation and systemic immunological processes, thus augmenting recovery.
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Statistics Of Overall Improvement of Down Syndrome Through Stem Cell Therapy
We believe that there is always some hope and that patients deserve access to adequate and safe treatments. We are independent with an internal medicine division. We combine worldwide accredited hospitals, the next-generation stem cell treatment for muscular dystrophy, and unique products and services that are integrative and effective to safeguard optimal treatment outcomes.
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Down Syndrome FAQs
How can the diagnosis be done after birth?
A diagnosis can be done on the basis of the facial features and deferred development which are typical of Down’s syndrome. Along with that, a chromosomal analysis known as the Karo type test can ratify the diagnosis of Down’s syndrome post-birth.
When is the correct time to seek intervention for a child diagnosed with Down’s syndrome?
The intervention can begin instantaneously after the diagnosis of the syndrome in the kid. Timely intervention helps the young kid to attain his optimum level of development more rapidly.
Will the other kid also have Down’s syndrome?
It is imperative for the parents to undergo genetic counseling so as to determine the risk when they plan for a second child. However, there are no identified behavioral or environmental reasons pertaining to Down’s syndrome.
Are children with Down’s syndrome only born to older parents?
80% of kids with Down’s syndrome are born to females younger than 35. However, the likelihood of the kid having the syndrome does upsurge with maternal age.
Can the child get married and have kids in the future? What are the probabilities of the baby having Down’s syndrome?
A kid with Down’s syndrome can get married and have children, as around 50% of all women with Down’s syndrome are fertile and have regular menstrual cycles. However, between 35 to 50 percent of kids born to mothers with Down’s syndrome have a probability of being born with Trisomy 21 or other developmental capacities.
Will the kid’s facial structure change after Stem Cell Therapy?
Stem Cell Therapy works on improving the brain functioning in the kid, so therefore, the facial features remain the same.
How many times is Stem Cell Therapy required for our child?
The number of times entirely depends upon the varied multiplicity of factors like the impairment in the brain and the severity of the condition. Whether another round of stem cell therapy is necessary or not. All this is determined on the basis of clinical follow-up and comparison of the PET-CT Scan 6 months after the first stem cell therapy. Depending on the outcome of all these investigations at the time of follow-up, the need for another shot is indicated.
Can there be any side effects of this treatment on the kid?
No side effects have ever been noted until now, as no foreign entity is inserted into the kid’s body.
Is there a chance of the kid’s condition worsening prior to the treatment?
This treatment does not cause any worsening in the condition of the kid as it works on boosting the development of the child.
Can stem cell therapy result in speech development in the child?
Improvement in the speech is noted in a maximum of cases. The range can be extended with some children going from monosyllabic speech to developing the aptitude to speak small sentences.
Can the child down with Down’s syndrome get better after stem cell therapy?
Stem cell therapy addresses the mutilation in the brain and boosts mental development. It does not concentrate on the physical problem but is associated with the conditions like hypothyroidism, heart problems, facial configuration, etc.
Down Syndrome Patient Stories
Abdur Khan From Dubai Came To India For His Son’s Down Syndrome Treatment
I had doubts about the treatment until I noticed the effect on my kid. He stopped having seizures, and his muscle tone improved. It has been 3 months since we started the treatment
Meher Randhawa Underwent Stem Cell Treatment For Down Syndrome
I tried stem cell therapy in India for my daughter, and I couldn’t be happier with the results. The doctors have been incredible, and the treatment is much less painful than we expected
Mrs. And Mr. Mark From UK Came To India For The Down Syndrome Stem Cell Treatment Of Their Baby
Our baby was born with Down syndrome and she had had subnormal motor skills. Once she was 3 years old, we decided to opt for stem cell therapy at Viezec in India. After the treatment,
Laila From Abu Dhabi Was Treated From Down Syndrome In India
After being spotted with Down syndrome at birth, Laila’s parents knew they are required to find a way to help their daughter attain a better quality of life. After a lot of futile efforts in their own native land
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Treatment Results Of Down Syndrome at Viezec
Many pieces of research showed that stem cell therapy for Down syndrome in India still has much potential. After a little more research, they believe that these stem cells could even be able to replace the genetically malfunctioning cells. Until then, we advise every parent to bring their child with Down syndrome for the most advanced stem cell treatments administered at Viezec Stem Cell Institute, and we have had excellent results in the past.
Many patients with down syndrome that have been injected with stem cells in the past also state that they could feel the pace at which their mental capacity was improving, and they also demonstrated the physical activities that they couldn’t perform in the past.
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With the team of Viezec, every patient gets a certified and authentication quantity of stem cells for the treatment. Then, before the transplantation process, a small allocation of your blood, bone marrow, or other microorganisms, which will be needed at the time of therapy, is transferred to a certified research facility for the separation and improvement of the cells.
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Follow-up Seen After the Stem Cell Therapy for Down Syndrome
The Staff at Viezec, India, will call you in one month, two months, and a half years to see the improvement of the treatment. This encourages us to refine our conventions to improve further. You can likewise require some other assistance on the off chance that is required. We offer Stem cell treatment for Down Syndrome in Delhi, India.