What is Down Syndrome?
Down Syndrome is a most common condition related to chromosomes and genetics. Individuals with Down syndrome are born with an additional pair of 21st chromosomes, which causes intellectual disabilities and developmental delays.
It is a hereditary condition where several disabilities are lifelong and can also reduce your expectation of life. In the mild to moderate range of this condition, children with down syndrome have intellectual delays and disabilities. They can also suffer from various medical issues like congenital heart issue, which occurs during the pregnancy of the mother.
The maximum number of babies born with this state acquired an extra copy pair of chromosomes 21, with an additional three copies of the chromosome, rather than having the usual two, which leads to some physical and mental challenges over the course of their whole life.
However, many experts have discovered or invented various support treatments and medications to help people with down syndrome. So, if someone is searching for an affordable, safe, and effective treatment, they can consider choosing stem cell therapy for down syndrome in India. Our doctors at Viezec will guarantee you will provide several opportunities and hopes to overcome the difficulties of down syndrome.
Causes of Down Syndrome
Man tissue regularly consists of 23 groups of chromosomes. 1 chromosome in each set comes from your father and the other from your mommy. This extra genetic substance is liable for the brand illustrates and formative problems of the Lower condition. Any kind of three genetic versions may cause a condition:
Trisomy 21. Close to 95 percent of the time, a down ailment is a result of trisomy 21; the average person has three duplicates of chromosome 21, rather than regular two duplicates, in all of the tissue. This can be a result of strange cellular sections through the enhancement of the sperm cellular or maybe the ovum cellular.
Mosaic Down problem. Within this uncommon form of Down disorder, someone has only a few tissues with further identification of chromosome 21. This mosaic of every day and abnormal cells is caused by the strange cellular departments after treatment.
Translocation Down problem. the down ailment can likewise occur when a little bit of chromosome 21 becomes signed up with (translocated) onto another chromosome, previously or at origination. These teenagers have the typical two duplicates of chromosome 21, but they likewise have added inherited materials from chromosome 21 to become a member of another chromosome.
Symptoms Associated with The Down Syndrome
As discussed above, down syndrome causes mental and physical developmental delays and disabilities. However, the signs and symptoms may vary depending on the types and stages of the condition.
Symptoms of physical disabilities might include the following:
- Defective muscle tone
- Tiny ears and head
- Flat facial structures
- The short and bulky physical proportions
- Petite neck
- Eyes with almond-shaped structure
- Little feet and hands
Common symptoms of behavioral and learning delays comprise:
- Halts in language and speech development
- Attention issues
- Unable to sleep properly
- Delay learning capability to talk and walk
- Stubbornness and temper hysterics
What Are the Tests to Down Syndrome Diagnosis
A doctor may suspect Down syndrome in a newborn based on the baby’s appearance. A blood test can confirm that called a karyotype test that lines up the chromosomes and will show if there’s an extra chromosome 21.
Down Syndrome Screening in Pregnancy
Routine tests done during pregnancy can check if it’s likely your baby has Down syndrome. If those results are positive, or if you’re at high risk, you may choose to have additional, more invasive tests, to be specific.
In the first trimester, you may have:
- Blood tests. Your doctor will measure the levels of a protein called PAPP-A and a hormone called hCG in your blood. Anything out of the normal range could mean a problem with the baby. If you’re at high risk for Down syndrome, they may also look for DNA from the baby in your blood, which they can examine for chromosome abnormalities.
- Your doctor will look at a picture of your baby and measure the folds of tissue at the back of their neck. Babies with Down syndrome tend to have extra fluid there.
In the second trimester, you may have:
- Blood tests. A triple or quad-screen test measures other substances in your blood, including the protein AFP and the hormone estriol. Those levels, combined with the results from the first trimester tests, give your doctor a reasonable estimate of your baby’s chances of Down syndrome.
- When your baby is more developed, an enhanced ultrasound can show some of the physical features of Down syndrome.
Other kinds of tests can diagnose Down syndrome before your baby is born by checking a sample of their DNA for an extra chromosome 21:
- Chorionic villus sampling (CVS). This can be done during the first trimester using cells taken from the placenta.
- Fluid is taken from the amniotic sac surrounding the baby, usually during the second trimester.
- Percutaneous umbilical blood sampling (PUBS). This is also done in the second trimester using blood removed from the umbilical cord.
Kindly share the following test reports of
- Chromosomal Karyotyping (trisomy 21 karyotype Testing)
Stem Cell Therapy for Down Syndrome
Over the past few years, the popularity of stem cell therapies has remarkably increased. The medical is utilising this treatment to cure various diseases like neurodisorder conditions, orthopedic disease, eye disorders, and many more, including down syndrome.
For stem cell therapy for down syndrome in Delhi NCR, Viezec doctors extracted adult cells known as mesenchymal stem cells from either the adipose tissue or the umbilical cord tissue from the individual’s body. In addition to this treatment, we conjoint some supportive therapies like occupation therapy, speech therapy, physical therapy, and behavioral therapy for the patients so that they can recover from the condition in no time. Stem cell therapy may not completely cure the disorder, but it will surely give you a better life as it will slow down the progression of the disease.
Stem Cell Implantation for Down Syndrome
Stem cells possess an exceptional ability to split and replicate themselves, as well as the ability to transform into several specialized cell types as required by the body. During the implantation process, the following steps are followed:
- Liberation angioplasty
- Surgical administration
- Intravenous administration
Improvements Seen After the Stem Cell Therapy for Down Syndrome
If the baby is born with an additional pair of chromosome 21, it can result in a condition called down syndrome. It is characterized by mental retardation, low muscle tone, an upward slant to the eyes, and a characteristic broad flat facial structure. However, currently, there is no known cure for Down syndrome. Medical research has shown that stem cell treatments can help improve conditions related to this very rare disorder, suggesting that there is hope that people with Down syndrome can be cured one day. Until then, they are using stem cells can at least lead to better lives, even if there isn’t a lasting solution.
Mechanism of Down Syndrome
There are various alternative medical treatment approaches, such as stem cell therapy which can help you to manage the symptoms associated with Down syndrome and will assist the patients in enhancing their intellectual and physical capability of the kid so that they can easily live a quality life.
Researchers and doctors hope stem cell studies can help to increase awareness about how illnesses arise. Researchers and studies suggested that experts may know and understand the reason that stem cells can grow themselves and become whole new bones, muscles, nerves, and other organs by replacing the damaged and injured cells.
Cellular therapy using autologous bone marrow derived from mononuclear cells has been proposed as a treatment approach that befits numerous neurological ailments. These cells have the propensity to migrate and offer repair mechanisms such as endogenous neurogenesis, angiogenesis, and synaptogenesis of the impaired neurons. Along with that, stem cell therapy helps significantly decrease inflammation and systemic immunological processes, thus augmenting recovery.
Statistics Of Overall Improvement of Down Syndrome Through Stem Cell Therapy
We believe that there is always some hope and that patients deserve access to adequate and safe treatments. We are independent with an internal medicine division. We combine worldwide accredited hospitals, the next-generation stem cell treatment for muscular dystrophy, and unique products and services that are integrative and effective to safeguard optimal treatment outcomes.
Down Syndrome FAQs
- What is the longevity of an individual with Down Syndrome?
According to various studies and experts, the life expectancy of a person is approximately 60 years. However, in rare cases, it may vary from person to person and the types of down syndrome.
- What are the classifications of down syndrome?
Three types of down syndrome are there, which consists of:
- Trisomy 21
- Which organ of the body is most affected by down syndrome?
The most affected body organ is the heart. The majority of babies who has down syndrome have congenital heart disease.
- Is Down Syndrome painful?
Down syndrome can cause intellectual disabilities as the condition is related to hereditary and is highly linked with a painful physical state like neck and hip pain.
Down Syndrome Patient Stories
I had doubts about the treatment until I noticed the effect on my kid. He stopped having seizures, and his muscle tone improved. It has been 3 months since we started the treatment
I tried stem cell therapy in India for my daughter, and I couldn’t be happier with the results. The doctors have been incredible, and the treatment is much less painful than we expected
Our baby was born with Down syndrome and she had had subnormal motor skills. Once she was 3 years old, we decided to opt for stem cell therapy at Viezec in India. After the treatment,
After being spotted with Down syndrome at birth, Laila’s parents knew they are required to find a way to help their daughter attain a better quality of life. After a lot of futile efforts in their own native land
Treatment Results Of Down Syndrome at Viezec
Many pieces of research showed that stem cell therapy for Down syndrome in India still has much potential. These stem cells have a unique and special ability to restore injured and damaged cells and also can able to regenerate these cells into brand-new healthy cells so that your symptoms related to the condition can slow down over time.
. Until then, we advise every parent to bring their child with Down syndrome for the most advanced stem cell treatments administered at Viezec Stem Cell Institute, and we have had excellent results in the past.
Many of our past patients who have undergone stem cell therapy for down syndrome in India have stated that they can observe and experience that their mental capacity for doing anything is improving day by day and they are very happy with the results, and they also demonstrated the physical activities that they couldn’t perform in the past.
With the team of Viezec, every patient gets a certified and authentication quantity of stem cells for the treatment. Then, before the transplantation process, a small allocation of your blood, bone marrow, or other microorganisms, which will be needed at the time of therapy, is transferred to a certified research facility for the separation and improvement of the cells.
Follow-up Seen After the Stem Cell Therapy for Down Syndrome
The Staff at Viezec, India, will call you in one month, two months, and a half years to see the improvement of the treatment. This encourages us to refine our conventions to improve further. You can likewise require some other assistance on the off chance that is required. We offer Stem cell treatment for Down Syndrome in Delhi, India.