Exosome Therapy: A New Periphery in Regenerative Medicine

In recent years, exosomes have been increasingly recognised as an efficient and safe way to deliver treatments, leading to a new form of regenerative medicine. Exosomes provide a novel means for drug delivery through their involvement in the communication and rejuvenation of cells in the body. Further in this post, we’ll discuss about exosome and their role in preventing any medical conditions in detail.

Synopsis of Exosome Therapy

The term “regenerative medicine” is gaining traction in the medical world. This is due to its ability to tap into the body’s natural capability to heal itself. By leveraging this intrinsic ability, regenerative therapies can help improve the body’s overall health and well-being.

Exosome therapy is an effective and versatile approach to treating medical conditions such as osteoarthritis, chronic pain, and musculoskeletal trauma. It helps to restore the communication between cells that may be affected by genetic disorders, chronic diseases, and the natural ageing process. By re-establishing cellular communication, exosome therapy encourages the healing process.

Now that you know the basic definition of exosome therapy, let’s understand the perks of using it for the treatment of various conditions. But before that, you should know what exactly exosome is and how they are extracted.

What are Exosomes?

Exosomes are a type of extracellular vesicle found in the external environment and are about 30-150 nm in size, making them the smallest known vesicle. They are enveloped by a lipid bilayer and contain a wide range of components from the original cell, such as proteins, lipids, mRNA, miRNA, and DNA.2 Exosomes are distinguished by how they are formed – through the fusion and exocytosis of multivesicular bodies into the outside environment.

Process of Generating Exosomes

Multivesicular bodies (MVBs) are a specialised subset of endosomes that contain membrane-bound intraluminal vesicles. These vesicles form by budding into the lumen of the MVB and can then be released into the extracellular space as exosomes when the MVB fuses with the plasma membrane. Most intraluminal vesicles, however, are connected with lysosomes for degradation.
Currently, the regulation of exosome release has yet to be fully understood, but recent imaging techniques may allow researchers to observe exosome release events more closely.

Working Mechanism of Exosome Therapy

Exosomes act as a vehicle, transporting messenger RNA to other cells. These exosomes contain healthy cells inserted into the target cells, releasing new and young stem cells with powerful regenerative capabilities. In addition, the stem cell exosomes contain valuable cellular components such as proteins and genetic material that help ensure the proper functioning of the receiving cells.

Exosome therapy transfers NK cells (Killer cells) into T-Regulator cells (helper cells) to help regulate an overly reactive immune system. This treatment is typically administered as an outpatient procedure. The process of exosome transfer assists in restoring coordination to the immune system, helping it to function optimally.

The Benefits of Exosome Therapy in Treating Multiple Disease

Here are a few primary advantages of this treatment in the field of regenerative medicine:

  • Decreased inflammation: Inflammation is the body’s way of fighting infections, but chronic inflammation can lead to DNA damage, tissue death and scarring. Exosome therapy can reduce inflammation by prompting cells to reset, repair and regenerate.
  • Enhance brain health: Aging & damaged brain cells can negatively impact cognitive function. Exosome therapy signals cells to regenerate & repair, improving alertness, mental performance & clarity.
  • Aid metabolic activity: Exosome therapy boosts cell metabolism, aiding weight loss, enhancing muscle tone and increasing energy levels by recharging the body’s metabolic function.
  • Slow down chronic pain: Chronic pain has no benefit and disrupts daily life. Exosome therapy can reduce inflammation and, thus, pain by targeting origin cells and encouraging healing and regeneration.
  • Intensify tissue regeneration: Aging is linked to tissue death; diet & exercise can slow it, but exosome therapy reverses it, resulting in new tissue growth & healthy cell regeneration.
  • Promoted immune health: A weak immune system invites infection. Exosome therapy strengthens cells, boosting the body’s defence against infection.

In Summary!

We suggest that patients who are looking for medical care reach out to Viezec Stem Cell Institute. Our mission is to provide advanced, thoroughly researched exosome therapy solutions with the goal of enhancing and restoring a patient’s quality of life. Or, if you’re interested in learning more about how the treatment can benefit your health, or if you’d like to discuss your condition, please contact us or book an appointment today.