What is Optic Nerve Hypoplasia?
Optic nerve hypoplasia (ONH) is a condition characterized by a decreased number of optic nerve axons. It can present unilaterally or bilaterally and may be associated with midline cerebral structural defects, such as septum pellucidum absence, agenesis of the corpus callosum, cerebral hemisphere abnormalities, or pituitary gland abnormalities. Individuals with ONH have abnormal eye actions, and vision can range from no light perception to good functional vision or even full vision in one eye.
A child with Optic Nerve Hypoplasia has underdeveloped optic nerves. This commonly occurs in both eyes, often with one eye worse than the other, but it can also occur in only one eye. The more links between the eye and the brain, the better the vision. Some people with Optic Nerve Hypoplasia have a near-normal idea in one eye, others have decreased vision in both eyes, and others are completely blind.
Prognosis for Optic Nerve Hypoplasia
Optic nerve hypoplasia (ONH) is a congenital disorder in which the optic nerve is underdeveloped. The severity of ONH can vary from mild to severe, and it can affect one or both eyes. In most cases, ONH is diagnosed at birth or during early childhood.
The prognosis for children with ONH depends on the severity of the condition. Most children with mild ONH will have normal vision. Children with moderate to severe ONH may have reduced vision or legal blindness. Some children with ONH may also have other health problems, such as hearing loss, developmental delays, or seizures.
Living with Optic Nerve Hypoplasia
If you have optic nerve hypoplasia (ONH), it means that your optic nerves didn’t develop properly while you were growing in your mother’s womb. As a result, you have reduced vision in both eyes. You may be born with ONH or it may develop later in childhood.
Most people with ONH have low vision, meaning they can see better with corrective lenses than without them. Some people with ONH are legally blind, which means their vision cannot be corrected to better than 20/200 or they have a visual field of less than 20 degrees even with corrective lenses.
There is no cure for ONH, but treatments can help improve vision and quality of life. For example, low vision aids such as magnifiers and special glasses can help make the most of remaining vision. Rehabilitation services can also teach children and adults how to adapt to living with reduced vision.
Viezec is a medical tourism company that specializes in helping patients find the best hospitals in India for their medical needs, including stem cell therapy for optic nerve hypoplasia. Based in Delhi, India, the company has a team of medical professionals who are familiar with the Indian healthcare system. They can help patients find the best hospitals that fit their budgets and conditions.
Causes of Optic Nerve Hypoplasia
The most common cause of optic nerve hypoplasia is a mutation in the gene PDE6C. This gene provides instructions for making an enzyme called phosphodiesterase 6C. This enzyme is involved in the development and function of rod cells, which are light-sensitive cells in the retina that play an important role in night vision. Mutations in PDE6C disrupt the normal function of this enzyme, resulting in fewer rod cells and reduced night vision.
Optic nerve hypoplasia can also be caused by mutations in other genes, including BMP4, SIX3, SIX6, and OTX2. These genes are involved in eye development and may help regulate the activity of PDE6C. Mutations in any of these genes can lead to abnormal development of the optic nerve and reduced vision.
In some cases, optic nerve hypoplasia occurs without a known genetic cause. The condition may be associated with certain medical conditions such as congenital rubella syndrome (a viral infection that can occur before birth), albinism (reduced pigmentation), or fetal alcohol syndrome (a condition caused by exposure to alcohol during pregnancy). Additionally, optic nerve hypoplasia may be caused by exposure to certain toxins or medications during pregnancy.
Symptoms Associated with Optic Nerve Hypoplasia
Optic nerve hypoplasia (ONH) is a congenital disorder in which the optic nerve is underdeveloped. The optic nerve is responsible for transmitting visual information from the eye to the brain, and so people with ONH typically have vision problems.
There are a few different symptoms that can be associated with optic nerve hypoplasia. The severity of these symptoms can vary from person to person, and not everyone will experience all of them. Some common symptoms include:
- Vision problems: This can range from mild issues like difficulty seeing in low light, to more severe issues like complete blindness.
- Eye movements: People with optic nerve hypoplasia may have trouble moving their eyes side to side, or up and down. This can make it difficult to track objects or read.
- Nystagmus: This is a condition where the eyes make repetitive, uncontrolled movements. It can be very distracting and can make it difficult to see clearly.
- Photophobia: This is a heightened sensitivity to light. People with photophobia may find bright lights painful or uncomfortable to look at.
What are the Tests to Diagnose Optic Nerve Hypoplasia
When it comes to diagnosing optic nerve hypoplasia, there are a few things that need to be taken into account. First and foremost, it is important to rule out any other potential causes of vision loss. Once other causes have been ruled out, your doctor will likely order a brain MRI. This imaging test can help to confirm the diagnosis of optic nerve hypoplasia.
In some cases, a doctor may also recommend genetic testing. This can be helpful in determining if there is a family history of optic nerve hypoplasia or if there is a specific genetic mutation that is associated with the condition.
Once a diagnosis of optic nerve hypoplasia has been made, your doctor will work with you to develop a treatment plan. This may include things like glasses or contact lenses, medication, surgery, or therapy.
There is no single test for diagnosing ONH. Instead, doctors will often use a combination of tests to get a better understanding of the condition. This may include:
- A complete eye exam
- A scan of the optic nerve ( OCT )
- A visual field test
- An MRI of the brain
Stem Cell Treatment for Optic Nerve Hypoplasia
Optic nerve hypoplasia is a congenital disorder of the optic nerve, which is the bundle of nerves that transmits visual information from the eye to the brain. The disorder results in poor vision, and in severe cases, blindness. There is no cure for optic nerve hypoplasia, but treatment options are available to improve vision.
One treatment option for optic nerve hypoplasia is stem cell therapy. A stem cell is an undifferentiated cell that can differentiate into various types of cells, such as nerve cells. In stem cell therapy for optic nerve hypoplasia, stem cells are injected into the optic nerve. The stem cells then differentiate into healthy nerve cells and help to repair the damage caused by the disorder.
There is no cure for ONH, but stem cell treatment may be a promising option for managing the condition. In a small study of children with ONH, stem cells were injected into the affected eye. The children in the study showed significant improvements in visual function after treatment.
Stem cell therapy is a promising treatment option for optic nerve hypoplasia, but it is still in its early stages of development. More research is needed to determine its safety and efficacy.
How does stem cell therapy work for Optic Nerve Hypoplasia?
Optic nerve hypoplasia (ONH) is a congenital disorder characterized by the underdevelopment of the optic nerve. The optic nerve is responsible for transmitting visual information from the eye to the brain, and people with ONH typically have reduced vision in both eyes.
There is no cure for ONH, but stem cell therapy has shown promise as a treatment option. Stem cells are undifferentiated cells that have the ability to differentiate into various types of cells, including nerve cells. Injecting stem cells into the optic nerve has been shown to improve vision in animal models of ONH.
This treatment could provide hope for people with this condition who have very few treatment options available to them at present.
How much Stem cell therapy cost for Optic Nerve Hypoplasia?
Optic nerve hypoplasia (ONH) is a congenital disorder characterized by a underdeveloped optic nerve. It is one of the most common causes of visual impairment in children, and can lead to complete blindness. There is no cure for ONH, but stem cell therapy is emerging as a potential treatment option.
Stem cell therapy for ONH involves injecting healthy, functional stem cells into the affected eye. These stem cells then replace the damaged cells and help to restore vision. The cost of stem cell therapy for ONH varies depending on the severity of the condition. It is important to remember that ONH is a lifelong condition and there are no other treatment options available. For many people, stem cell therapy is the best chance at regaining some level of vision.
The exact cost will vary depending on the individual’s condition and the treatment plan. Some insurance companies may cover part or all of the cost of stem cell therapy.
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Stem Cell Implantation for Optic Nerve Hypoplasia
At the Viezec Stem Cell Institute, the implantation stage of stem cell therapy for Optic Nerve Hypoplasia is of utmost importance. The structure that is followed during this stage is as follows:
- Intravenous administration
- Intrathecal (lumber puncture)
- Liberation angioplasty
- Surgical administration
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The purpose of our stem cell treatment is to reinstate neurological function in the brain/spinal cord lesion region, thus, plethora of improvements are suitable and can be opted after the treatment, the previous patients have shown signs of following:
- Improved visual insight
- Improved light perception
- Enlarged visual field
- Perkier night vision
- Abridged nystagmus
- Enriched strabismus
- Better-quality hormonal deficiencies
- Reduced autistic symptoms
It is vital and imperative to remember that as for any medical treatment, improvements cannot be promised. Please contact us for more info, regarding the possible improvements for any specific case. If you are looking for assistance with Optic nerve hypoplasia stem cell treatment in India, trust ViezecMedicalHealthCare, to provide you the best treatment.
Mechanism of Optic Nerve Hypoplasia
The stem cells that are used for the treatment of optic nerve hypoplasia are mesenchymal stem cells. Viezec Stem Cell Institute has successfully executed stem cell treatment on patients with expert care and precautions. These stem cells have been used to cure ONH and SOD (Septo-optic dysplasia).
The capacity of mesenchymal stem cells (MSCs) to differentiate into neural cells and to secrete neurotrophic factors, such as brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factors (GDNF), which may promote the differentiation of grafted cells into neural cells, prevent apoptosis, enhance angiogenesis, suppress inflammatory infiltrates and sustain grafted cells.
These pathways not only help to maintain vision, but they also help to enhance significantly vision loss by the optic nerve and retinal ganglion cell regeneration.
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Statistics Of Overall Improvement of Optic Nerve Hypoplasia Through Stem Cell Therapy
At Viezec Stem Cell Institute, we believe there are always possibilities and hope patients deserve access to safe and effective stem cell therapy for erectile dysfunction. We aim to provide you with the best hospitality experiences by attending to our patients and their families in many ways. Our staff consists of specialists who are familiar with treating patients. With a team of experts and assistants, we can provide top-quality services to all guests under one roof for their convenience.
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Optic Nerve Hypoplasia FAQ’s
Is optic nerve damage a disability?
Optic nerve hypoplasia (ONH) is a congenital disorder in which the optic nerve doesn’t develop properly. This can lead to vision problems and, in some cases, blindness.
ONH is considered a disability because it can cause significant vision impairment and may prevent someone from being able to work or participate in activities of daily living. In addition, people with ONH may need special accommodations in order to be able to function optimally.
Can optic nerve hypoplasia cause blindness?
Optic nerve hypoplasia (ONH) is a congenital condition in which the optic nerve is underdeveloped. This can lead to decreased vision and, in severe cases, blindness.
There are many different causes of ONH, but the most common is a genetic mutation. Other causes include exposure to certain toxins or medications during pregnancy, or damage to the optic nerve after birth.
Most people with ONH have at least some vision, but those with severe ONH may be blind. Treatment typically focuses on managing symptoms and maximizing remaining vision. In some cases, surgery may be an option.
What does a person with optic nerve hypoplasia see?
A person with optic nerve hypoplasia sees reduced detail and vision in dim light. The severity of the condition can vary, but most people with this condition have legal blindness.
Does optic nerve hypoplasia get worse over time?
There is no definitive answer to this question as optic nerve hypoplasia can vary greatly in terms of severity and progression. However, it is generally thought that the condition does not typically worsen over time. In some cases, children with optic nerve hypoplasia may experience a gradual decline in vision as they get older, but this is usually not a significant decrease. Additionally, many people with optic nerve hypoplasia are able to adapt and live relatively normal lives despite their visual impairment.
When is optic nerve hypoplasia diagnosed?
Optic nerve hypoplasia is usually diagnosed during infancy or early childhood. In some cases, it may not be diagnosed until adulthood. There are several ways to diagnose optic nerve hypoplasia. One way is to do a visual evoked potential test. This test measures the electrical activity in the brain in response to visual stimuli.
Another way to diagnose optic nerve hypoplasia is with an MRI. This can show the size and structure of the optic nerves.
If you suspect that you or your child has optic nerve hypoplasia, see an eye doctor as soon as possible.
Treatment Results Of Optic Nerve Hypoplasia at Viezec
Through stem cell therapy by Viezec, improvements can be seen in the symptoms of the patients. The main motive of stem cell therapy for ONH is to renew the neurological function in the brain/spinal cord, which was earlier disrupted. After stem cell treatment, significant improvements can be seen in the patients. Most patients with optic nerve disorders suffer from optical acuity, visual field, light sensitivity, night vision, strabismus, and nystagmus; therapies using mesenchymal stem cells demonstrated good progress. In comparison, treatment with stem cells has led to a substantial slowdown in vision deterioration in patients with advanced conditions.
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Optic Nerve Hypoplasia Patient Stories
Jaysingh from Patna underwent stem cell treatment to treat optic nerve hypoplasia
I was looking for a stem cell treatment for my baby, and I found this. It’s effective and affordable, and the results are outstanding. After my treatment, I was able to experience better vision capabilities,
Sadie Buyers from Texas visited India for stem cell therapy to treat optic nerve hypoplasia
Hi, I am George Buyers, father of Sadie Buyers. My daughter has optic nerve hypoplasia, and for the past several years, we have been looking for an effective and safe treatment method for my kid. But every time, we only get rejection
Belli Came To India For The Treatment Of Optic Nerve Hypoplasia Via Stem Cells
Belli lost her sight in a matter of weeks in 2014 because of a severe case of optic neuritis – inflammation of an optic nerve that causes gradually blurry vision as the nerve could no longer interconnect with the brain
Katie Came To India For Stem Cell Treatment Of Optic Nerve Hypoplasia
Katie is a 4 year old kid and she traveled to India with her parents so as to get stem cell treatment for optic nerve hypoplasia. Katie was first treated with stem cells in April of 2018 via Viezec.
Read More Optic Nerve Hypoplasia Patient Success Stories
Follow-up Seen After the Stem Cell Therapy for Optic Nerve Hypoplasia
The Viezec Stem Cell Institute team will take diligent follow-ups of the patient after the treatment. After regular intervals, follow-ups are done to understand the patients’ improvements and know if they are facing any issues
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Certificate of Analysis for Optic Nerve Hypoplasia Patient
Before the transplantation procedure, a few portions of blood, bone marrow, and other microorganisms that need treatment are sent to a certified research facility to separate and improve the cells.
At Viezec Stem Cell Institute, every patient gets a certified authentication number of cells for the process.
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Optic Nerve Hypoplasia Patient Video’s
A patient with Bilateral Toxic Optic Neuropathy shares her experience.. Watch Video
Mr.MD Anower Hossain – Bangladesh – Bilateral Toxic Optic Neuropathy Treatment.. Watch Video
Fazlolah Motaghi from Iran suffering from Toxic Optic Neuropathy for Stem Cell Treatment.. Watch Video
Father of Kunal Mondal Optic Neuropathy Age 17 Years Kolkata.. Watch Video
Optic Nerve Hypoplasia Stem Cell Therapy.. Watch Video
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