Motor neuron disease (MND) is a slow-progressing, deadly condition marked by the loss of anterior horn cells in the spinal column. Various treatment methods have been tried in the search for a cure over 150 years since it was originally reported, but with little success. Current conventional treatment barely extends patients’ lives by a few months; palliative care is their sole choice. Stem cell therapy is a promising therapeutic option for this deadly illness. A wide range of vitalizing effects, both paracrine and somatic, a good safety profile, and simplicity of availability all support the use of these cells for therapeutic reasons. This potent therapeutic method, when combined with intensive rehabilitation, has been proven to decrease disease progression, enhance quality of life, and increase survival in patients with amyotrophic lateral sclerosis (ALS)/MND, while also being well tolerated. There is compelling scientific and clinical evidence that stem cells have tremendous promise as an ALS/MND treatment. Stem cells have been shown to reduce and/or stop disease development in a fraction of ALS/MND patients, but they are not yet a final cure.
What is Muscular Dystrophy?
Muscular dystrophy is a category of illnesses characterised by gradual muscular weakening and loss. Mutations in faulty genes cause muscular dystrophy, which prevents the synthesis of proteins required to build healthy muscle.
Muscular dystrophy comes in a variety of forms. The most frequent variety’s symptoms appear in childhood, especially in males. Other kinds don’t show up till later in life.
Muscular dystrophy has no known cure. Medication and treatment, on the other hand, may help control symptoms and delay the progression of the illness.
What is the role of stem cell therapy for motor neuron disease and Muscular Dystrophy?
During a stem cell therapy session for motor neuron disease treatment in India, stem cells may participate in the following pointers:
-After separating into a distinct entity of brain cells, the stem cells are moved to aid in tissue repair. -An alternative to cells results in the production of stem cells.
-It increases the overall number of cells in the body.
-It provides a better living environment for motor neurons to continue to exist. -Motor neuron cells are better enhanced for protection, and it also transfers chemicals that serve as carriers.
Motor neuron disease develops when there is a significant rise in axonal degeneration of motor neurons in the spinal cord and motor cortex. The motor neurons, as well as the sensory system, are hindered as the illness progresses. Glial cells and stem cells play a multifaceted function in the regeneration of damaged motor neurons. A latent source of bone marrow cells may be used to regenerate neurons. It contains both haematological and mesenchymal progenitor cells, and it has the ability to move to the spinal cord and efficiently infuse the motor neuron disease area. Cellular therapy has long been shown to be a safe and effective treatment for motor neuron disease in India, where it is widely utilised.